Marcel Leist Selected Research

Amyloid beta-Peptides

4/2009	Measurement of cellular beta-site of APP cleaving enzyme 1 activity and its modulation in neuronal assay systems.
4/2007	Attenuated amyloid-beta aggregation and neurotoxicity owing to methionine oxidation.

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Marcel Leist Research Topics

Disease

20	Parkinson Disease (Parkinson's Disease) 11/2022 - 02/2004
7	Neurodegenerative Diseases (Neurodegenerative Disease) 11/2022 - 04/2003
6	Inflammation (Inflammations) 01/2020 - 08/2004
5	Alzheimer Disease (Alzheimer's Disease) 10/2018 - 05/2006
4	Neoplasms (Cancer) 01/2021 - 07/2002
4	Infections 01/2021 - 05/2002
3	Stroke (Strokes) 04/2008 - 05/2006
3	Ischemia 03/2007 - 11/2004
2	Hypersensitivity (Allergy) 01/2022 - 01/2006
2	Mitochondrial Diseases (Mitochondrial Disease) 01/2021 - 01/2020
2	Glioblastoma (Glioblastoma Multiforme) 03/2019 - 12/2002
2	Disease Progression 07/2014 - 04/2003
2	Schizophrenia (Dementia Praecox) 04/2007 - 01/2006
2	Infarction (Infarctions) 03/2007 - 11/2004
2	Hypoxia (Hypoxemia) 05/2006 - 11/2004
2	Necrosis 03/2005 - 01/2004
2	Huntington Disease (Huntington's Disease) 05/2004 - 04/2003
1	Hepatocellular Carcinoma (Hepatoma) 10/2022
1	Peripheral Nervous System Diseases (PNS Diseases) 03/2022
1	Hyperalgesia 01/2022
1	Chemical and Drug Induced Liver Injury 01/2021
1	Neuroblastoma 01/2021
1	Infectious Arthritis (Septic Arthritis) 01/2021
1	Leukemia 06/2020
1	COVID-19 01/2020
1	Hepatitis 01/2020
1	Metabolic Diseases (Metabolic Disease) 01/2020
1	Poisoning 01/2020
1	Rupture 03/2019
1	Cognitive Dysfunction 01/2018
1	Acute Kidney Injury (Acute Renal Failure) 01/2018
1	Chronic Renal Insufficiency 01/2018
1	Type 2 Diabetes Mellitus (MODY) 01/2018
1	Brain Neoplasms (Brain Tumor) 01/2018
1	Parkinsonian Disorders (Parkinsonism) 11/2015
1	Liver Diseases (Liver Disease) 12/2014
1	Fibrosis (Cirrhosis) 12/2014
1	Paralysis (Palsy) 11/2014
1	Neurodevelopmental Disorders 01/2014
1	Synucleinopathies 05/2013

Drug/Important Bio-Agent (IBA)

9	Proteins (Proteins, Gene)FDA Link 01/2021 - 12/2002
6	Erythropoietin FDA Link 04/2008 - 05/2003
5	SynucleinsIBA 01/2021 - 12/2011
5	alpha-SynucleinIBA 01/2019 - 12/2011
4	Pharmaceutical PreparationsIBA 06/2021 - 01/2018
4	CytokinesIBA 01/2020 - 05/2003
3	PesticidesIBA 01/2021 - 03/2017
3	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2020 - 01/2004
3	Peptides (Polypeptides)IBA 03/2019 - 04/2007
3	1- Methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP)IBA 01/2017 - 08/2015
3	Interleukin-6 (Interleukin 6)IBA 04/2007 - 08/2004
3	asialoerythropoietinIBA 11/2004 - 05/2003
2	Intrinsically Disordered ProteinsIBA 01/2021 - 12/2017
2	XenobioticsIBA 01/2020 - 12/2014
2	IronIBA 01/2020 - 07/2014
2	Dopamine (Intropin)FDA LinkGeneric 10/2018 - 12/2007
2	EnzymesIBA 10/2018 - 12/2014
2	Amyloid (Amyloid Fibrils)IBA 10/2018 - 08/2014
2	Glucose (Dextrose)FDA LinkGeneric 01/2018 - 03/2007
2	2,6-dinitrotoluene (DNT)IBA 07/2014 - 01/2014
2	Amyloid beta-PeptidesIBA 04/2009 - 04/2007
2	N-Methylaspartate (NMDA)IBA 03/2007 - 05/2006
2	3,9-bis((ethylthio)methyl)-K-252aIBA 03/2005 - 08/2004
2	Phosphotransferases (Kinase)IBA 03/2005 - 08/2004
2	HSP70 Heat-Shock Proteins (Heat-Shock Protein 70)IBA 04/2003 - 12/2002
1	Phenol (Carbolic Acid)FDA Link 11/2022
1	PhenolsIBA 11/2022
1	Glutathione (Reduced Glutathione)IBA 10/2022
1	Anti-Bacterial Agents (Antibiotics)IBA 10/2022
1	Nitrofurantoin (Macrodantin)FDA LinkGeneric 10/2022
1	Bortezomib (Velcade)FDA Link 03/2022
1	TRPV1 receptorIBA 01/2022
1	Voltage-Gated Sodium ChannelsIBA 01/2022
1	Levodopa (L Dopa)FDA LinkGeneric 06/2021
1	Inosine Diphosphate (IDP)IBA 01/2021
1	Nicotinic Receptors (Nicotinic Acetylcholine Receptor)IBA 01/2021
1	RNA (Ribonucleic Acid)IBA 01/2021
1	Technetium (Technetium 99m)IBA 01/2021
1	Ceftizoxime (Cefizox)FDA Link 01/2021
1	Amino Acids FDA Link 01/2021
1	NaphthoquinonesIBA 06/2020
1	lapacholIBA 06/2020
1	Chelating AgentsIBA 01/2020
1	VaccinesIBA 01/2020
1	Spider Venoms (Venom, Spider)IBA 03/2019
1	Antimicrobial PeptidesIBA 03/2019
1	DNA (Deoxyribonucleic Acid)IBA 03/2019
1	Peptide Hydrolases (Proteases)FDA Link 10/2018
1	SodiumIBA 01/2018
1	CanagliflozinIBA 01/2018
1	Sodium-Glucose Transporter 2 InhibitorsIBA 01/2018
1	NeurotoxinsIBA 11/2015
1	Biological ProductsIBA 12/2014
1	LigandsIBA 12/2014
1	Steroid 12-alpha-Hydroxylase (CYP8B1)IBA 12/2014
1	neurotoxic esteraseIBA 11/2014
1	Protein AggregatesIBA 05/2013
1	EpitopesIBA 11/2010

Therapy/Procedure

2	Therapeutics 07/2005 - 07/2002
1	Radiotherapy 01/2018